mastodon.ie is one of the many independent Mastodon servers you can use to participate in the fediverse.
Irish Mastodon - run from Ireland, we welcome all who respect the community rules and members.

Administered by:

Server stats:

1.6K
active users

#covidisnotover

56 posts48 participants3 posts today

From Germany:
"Given the importance of monocytes/macrophages system, YKL-40 may become a potential marker for the long-term dysregulation of the innate immune system"

archiv.ub.uni-heidelberg.de/vo

Screenshot from Science for ME weekly update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19

COVID-19 Made Our Brains Age Faster

The pandemic-era brains aged about 5.5 months faster compared to the brains of those studied before the pandemic. The accelerated aging was documented in people who had COVID-19 infections as well as those who didn’t:changes in gray and white matter were similar in people who were and were not infected.

However, only people infected with COVID-19 showed drops in cognitive skills.

time.com/7304417/covid-19-brai

Time · COVID-19 Made Our Brains Age FasterBy Alice Park

Hello Mastodon! 👋

My name is Delilah. (it's my online alias, not a legal name). I am a psychologist and youth counselor, and I mostly work with people suffering from personality disorders, eating disorders, and ASD/ADHD/ADD.

I have had teenage patients as well as adults and even families. In my career I even worked at schools but ended up abandoning that path due to constant defunding, where I no longer could help people without struggling to pay bills.

I will be posting mostly about how mental disorders work and to share some information about them. However I want to make it clear, that what I post should never be a substitute for actual medical consultation, and that I will not do therapy on social media.
I want to keep myself somewhat anonymous to not reveal my real-life identity, and to of course respect privacy laws related to my profession.

Outside of that, I like to keep myself up to date with technology and privacy, as it affects our mental health no matter how much we tend to deny this. I'm a cat mom of two, and love to tend to my mini-garden of vegetables.

I am not from USA, and English is not my first language, so please excuse my mistakes. I also ask to respect my privacy and be kind!

Looking forward to meeting new friends, and hopefully there are some profession peers on Mastodon?

Replied in thread

@augieray

2) People saying wastewater data isn't accurate.

Wastewater is accurate day-to-day. It may not be accurate variant-to-variant, and is certainly expected to vary within a given person by their vaccination and infection history. Support:

it remains challenging to directly translate wastewater SARS-CoV-2 viral loads to a specific number of infections in the population, due to the unclear fecal viral shedding rate (after accounting for the recovery rate of virus genomes) in wastewater samples. [4]

Eg:

In wastwater [...] Delta [...] had the highest mean shedding rates [...] while Omicron, exhibiting reduced symptoms, had the lowest mean shedding rates [1]

and

monovalent vaccination modified the time course and viral load of infections from different variants [2]

and

viral shedding duration differed significantly between BA.4/5 and BF.7 groups (p < 0.0001). [3]

and

Estimated fecal viral shedding rate was highest during the ancestral/Iota variant wave, at 1.44 (95% CI: 1.35 – 1.53) billion RNA copies in wastewater per day per infection (measured by RT-qPCR), and decreased by around 20% and 50-60% during the Delta wave and Omicron period, respectively. [4]

Which I take to mean that because of variant soup right now, and limited evidence specific to each variant (and kinetics and escape) and to immune histories (and waning), that we cannot translate directly from wastewater to case count. It is quite plausible to imagine, for example, a variant with half the fecal shedding taking over and causing wastewater to decline while cases increase - or with twice the fecal shedding taking over and causing wastewater levels to go up while cases drop.

[1] pmc.ncbi.nlm.nih.gov/articles/

[2] sciencedirect.com/science/arti

[3] frontiersin.org/journals/medic

[4] bmcpublichealth.biomedcentral.

PubMed Central (PMC)Variant-specific SARS-CoV-2 shedding rates in wastewaterPrevious studies show that SARS-CoV-2 waste shedding rates vary by community and are influenced by multiple factors; however, differences in shedding rates across multiple variants have yet to be evaluated. The purpose of this work is to build on ...

There are two non-fiction books that haunt me in the pandemic. The first is The Great Influenza: The Story of the Deadliest Plague in History (originally subtitled The Epic Story of the Deadliest Pandemic in History) by John M. Barry, about the 1918-1920 Spanish Flu pandemic.

It has made me feel particularly Cassandra-like in our own pandemic, because we absolutely know how pandemics work, how to manage them, and what goes wrong when we don't. 1/n

One of the books that made the biggest impressions on me as a kid was Flowers for Algernon (which I read far, far younger than was advisable as an advanced and voracious reader).

So I have to say that now living through an unacknowledged and unchecked pandemic that causes cognitive impairment and watching it steadily erode the people around me is a very particular kind of waking nightmare.

@bookstodon
#Bookstodon #CovidIsNotOver #PandemicIsNotOver #DanielKeyes #FlowersForAlgernon

Parents with sick kids are left with only bad choices because there's not enough support to keep sick kids home, be it for lack of sick leave or missing work hours and risking your job. We need a systemic approach that focuses on prevention, like clean indoor air, broader vaccine access and education about airborne transmission. This needs to go hand in hand with support measures that enable people to make the right choices. We need more sick leave, free RATs, normalise mask wearing etc
thepress.co.nz/nz-news/3607615

See ACA's petition and 11-point action plan for a sustainable solution:
our.actionstation.org.nz/petit

covidaction.nz/en/elevenpointp

#CovidNZ
#CovidIsNotOver
#LongCovid
#NZpol

www.thepress.co.nzThe Press
Continued thread

Raj's dashboard, updated Sunday, shows PQ.2 as standout child of Nimbus NB.1.8.1 / PQ; Stratus XFG overtaken by child XFG.2; and LP.8.1 long ago overshadowed by LP.8.1.1/ NY.

GISAID data for the most recent fortnight is dominated by submissions from New York (with all of 58 sequences), followed by Florida (with 17).

#CDC's most recent Friday dataset, updated Tuesday June 24, showed Nimbus taking plurality, with Stratus XFG family also gaining share.

FDA vaccine target LP.8.1, dominant since March, plateaued in April. June saw Nimbus NB.1.8.1 / PQ, scion of "razor-blade throat" XDV, push LP.8.1 out of majority.

#ThisIsOurPolio #variants #CovidIsNotOver #dataviz #datavis

Continued thread

Golden Age Karate was a Vimeo Staff Pick. They did a great interview with director Sinda Agha about the making of the film -- that also covers what it was like to film during the pandemic.

Whether you're a filmmaker yourself or a film fan who loves behind the scenes stories, it's a great read. 2/2

vimeo.com/blog/post/golden-age

@film
#SindaAgha #GoldenAgeKarate #VimeoStaffPick #Film #FilmMastodon #Filmmaking #CovidIsNotOver #PandemicIsNotOver

Staff Pick Premiere: "Golden Age Karate" by Sindha Agha and Zendesk
VimeoStaff Pick Premiere: "Golden Age Karate" by Sindha Agha and ZendeskFrom Zendesk and director Sindha Agha comes the heartwarming story of a teenage karate instructor and his class of hard-hitting senior citizens.