Satisfies in TypeScript
This is a post about one of TypeScript’s less common features: the satisfies keyword. It’s occasionally incredibly useful, and knowing how to properly wield it is a valuable trick to have up your sleeve. Let’s take a look!

Satisfies in TypeScript
This is a post about one of TypeScript’s less common features: the satisfies keyword. It’s occasionally incredibly useful, and knowing how to properly wield it is a valuable trick to have up your sleeve. Let’s take a look!
BESSER version 3.0 released
New major version of the #opensource #lowcode BESSER framework just released
Main New Features and Improvements:
Model (and generate) your #conversational #agents with our new BESSER Agentic Framework graphical editor
Enhanced #structural models with #metadata support - you can now add descriptions and URIs to classes
Improved the Python Generator to support generation of methods to handle bidirectional consistency in associations
Full details: https://github.com/BESSER-PEARL/BESSER/releases/tag/v3.0.0
Earthquake simulator to test 10-story steel-framed building
https://techxplore.com/news/2025-05-earthquake-simulator-story-steel.html
Fans were already gathering outside venue as Shakira & #Wyclef Jean concert cancelled in #Boston over #structural issues found at #FenwayPark.
,An upcoming Jason Aldean concert the next day at the famed Red Sox baseball #stadium has also been postponed due to problems found by inspectors checking portable stage construction.
https://www.cbsnews.com/boston/news/shakira-concert-boston-canceled-jason-aldean-fenway-park/
#structural : affecting structure
- French: structural
- German: strukturell
- Italian: strutturale
- Portuguese: estrutural
- Spanish: estructural
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Report an incorrect translation @ https://wordofthehour.org/r/translations
(27 Mar) Study of Lyft rideshare data confirms minorities get more tickets
Researchers ascribe it to “animus or prejudice against minority drivers.”…
https://s.faithcollapsing.com/erx1l
Archive: ia: https://s.faithcollapsing.com/swf2q
#bias #minorities #science #speeding-tickets #structural-racism #tickets #traffic-violations
#Germany’s economy still faces massive #structural challenges, chart @FT https://www.ft.com/content/ee20978f-bbcd-4616-954c-7749dc5334fd
PyForestScan - A Python Library For Calculating Forest Structural Metrics From LiDAR Point Cloud Data
--
https://doi.org/10.21105/joss.07314 <-- shared paper
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https://github.com/iosefa/PyForestScan <-- GitHub repository
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[disclaimer: I have not tried this library]
#GIS #spatial #mapping #JOSS #remotesensing #LiDAR #pointcloud #forest #structural #metrics #spatialanalysis #geostatistics #ecology #ecological #FHD #PAD #PyForestScan #model #modeling #opensource #Python #library #density #canopyheight #areaindex #DTM #output #PDAL #forest #forestry #monitoring #carbonaccounting
#structural : affecting structure
- French: structural
- German: strukturell
- Italian: strutturale
- Portuguese: estrutural
- Spanish: estructural
------------
Report an incorrect translation @ https://wordofthehour.org/r/translations
"RNA-Puzzles Round V dives into blind predictions by 18 modeling groups for 23 #RNA structures.
From #aptamers to #riboswitches, it highlights progress and challenges in RNA #3D #modeling.
Proud to contribute to this incredible journey! A heartfelt thank you to the organizers, collaborators, and the amazing community advancing RNA #structural #biology.
Together, we’re pushing the boundaries of #RNA3D, #StructuralBiology, #Bioinformatics, and #ComputationalBiology.
Pyramidal cell types and 5-HT2A receptors are essential for #psilocybin's lasting drug action https://www.biorxiv.org/content/10.1101/2024.11.02.621692v1 on #structural #neural #plasticity #neuroscience
"We find that a single dose of psilocybin increased the density of dendritic spines in both the subcortical-projecting, pyramidal tract (PT) and intratelencephalic (IT) cell types."
Hey! Please have a look at my lecture slides on 𝘉𝘢𝘺𝘦𝘴𝘪𝘢𝘯 𝘚𝘵𝘳𝘶𝘤𝘵𝘶𝘳𝘢𝘭 𝘝𝘦𝘤𝘵𝘰𝘳 𝘈𝘶𝘵𝘰𝘳𝘦𝘨𝘳𝘦𝘴𝘴𝘪𝘰𝘯𝘴 with the application to a small model for Aussie monetary policy using my 𝗥 package 𝗯𝘀𝘃𝗮𝗿𝘀!
https://bsvars.github.io/2024-10-be24-bsvars
#bsvars #rstats #structural #causaleffects
Makerpipe Turns Conduit Into Structures https://hackaday.com/2024/09/27/makerpipe-turns-conduit-into-structures/ #structural #connector #conduit #fitting #Parts #frame #beam #pipe #EMT
Makerpipe Turns Conduit Into Structures - At the risk of stating the obvious, building big things can be difficult. Sure, pa... - https://hackaday.com/2024/09/27/makerpipe-turns-conduit-into-structures/ #structural #connector #conduit #fitting #parts #frame #beam #pipe #emt
#Structural and #virologic #mechanism of the emergence of #resistance to #Mpro #inhibitors in #SARS-CoV-2, PNAS: https://www.pnas.org/doi/abs/10.1073/pnas.2404175121?af=R
We generated SARS-CoV-2 variants resistant to three SARS-CoV-2 main protease (Mpro) inhibitors (#nirmatrelvir, TKB245, and 5h), by propagating the ancestral SARS-CoV-2WK521WT in VeroE6TMPRSS2 cells with increasing concentrations of each inhibitor and examined their structural and virologic profiles.
Fancy a cuppa?
Thanks to Tong et al., we now have a much better understanding of the #genetic diversity, domestication, and #structural variations associated with #tea adaptation.
https://doi.org/10.1111/jipb.13737
@wileyplantsci
#PlantSci #ecology #evolution #phenotype #botany
Limitarianism: why we need to put a cap on the super-rich
Suppose you worked 50 hours a week between the ages of 20 and 65
– week in week out, year in year out
– how much would your hourly wage need to be so that by the end you had amassed Musk’s wealth?
The answer is: $1,871,794 per hour.
Almost two million dollars per hour. Every working hour for 45 years.
Elon Musk might be seen as exceptional, but there were 2,668 other billionaires on that Forbeslist.
Together they held $12,700,000,000,000.
Do you, like me, see all those zeros dancing before your eyes?
That’s because we don’t know how to take in that number.
On average the value of their assets is $4.75bn.
If we ask the same question again
– what’s the average lifetime hourly wage?
– we get $40,598 per hour, the equivalent to what many Americans hope to earn in a year.
How much is too much?
When I started this research, 10 years ago, several of my colleagues
– professors in philosophy, economics and related disciplines
– were initially amused that I wanted to delve into this question.
Some argued that #poverty was what mattered, not #inequality.
A few felt that focusing on the rich was an indication of envy on my part.
But I wasn’t alone.
Across various disciplines, scholars were starting to see that something was happening at the upper levels of society,
and we ought to pay attention.
I started to think through the #ethics of extreme wealth concentration in a systematic way,
and after a decade I became convinced that we must create a world in which no one is super-rich
– that there must be a cap on the amount of wealth any one person can have. I call this #limitarianism.
As a concept, limitarianism is simple.
But what does it mean in practice?
My book endeavours to answer that question, but it can best be understood as a regulative ideal
– an outcome to strive for but which, like the eradication of poverty, is unlikely to be definitively achieved.
In practical terms, limitarianism calls for three kinds of action. First there is #structural action. Our societies’ key social and economic institutions should give people genuinely equal opportunities, through
affordable childcare, free high-quality education and a comprehensive anti-poverty strategy.
The more structural steps we take to reduce inequality, the less need there will be for the second strategy:
fiscal action.
If taxation were our only tool for achieving a limitarian society, the tax rate would need to be set at 100% for wealth and income beyond a certain point
(spoiler alert: it is not the only tool).
Still, there is a very strong case for imposing a cap on extreme wealth.
The third kind of action limitarianism calls for is ethical action: we all need to embrace a limitarian ethos.
One objection to this might be that limiting how much wealth a person can accrue would require us to give up private property or the market mechanism, and force us into USSR-style communism.
Such an objection is nonsense,
and it’s probably just another attempt to silence meaningful criticism of the status quo.
Markets are a very powerful tool for securing material welfare;
private property is a cornerstone of our security, autonomy and prosperity.
The real question, which we must seek to answer, is rather which constraints on the market and private property we need if we are to achieve limitarianism.
#Structural #basis of #mpro of #MERS-CoV bound to antineoplastic #drug #carmofur, Biochem Biophys Res Commun.: https://www.sciencedirect.com/science/article/abs/pii/S0006291X24010052?via%3Dihub
Highlights:
* The crystal structure of MERS-CoV Mpro in complex with carmofur.
* The structural basis of MERS-CoV Mpro binding to the inhibitor carmofur.
* Structural comparison of carmofur with SARS-CoV-2 Mpro and MERS-CoV Mpro.
#Structural #Mapping of #Polyclonal #IgG Responses to #HA After #Influenza Virus #Vaccination or #Infection, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.08.601940v1
These data establish a baseline for assessing polyclonal #antibody responses in vaccination and infection, providing context for future vaccine #trials and emphasizing the importance of carefully designing vaccines to boost protective responses towards conserved epitopes.
#Structural and #functional characterization of avian #influenza #H9N2 virus #neuraminidase with a #combination of five novel #mutations, Arch Biochem Biophys.: https://www.sciencedirect.com/science/article/abs/pii/S0003986124001607?via%3Dihub
We report combination of novel mutations near the NA active site of an H9N2 strain. The mutations altered surface properties leading to increased substrate binding.