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#hydroxychloroquine

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Public
Levka

#HHS #hydroxychloroquine #quackery

"Steven J. Hatfill, a virologist and White House adviser during President Donald Trump’s first term who pushed hydroxychloroquine as a treatment for the coronavirus despite what most researchers said was a lack of scientific evidence, has joined the second Trump administration in a senior role at the Department of Health and Human Services.

(. . .)

Hatfill criticized coverage in The Washington Post and other publications of a study by Veterans Affairs researchers of 368 patients — all male with a median age over 65 — hospitalized with coronavirus infections. The study found no evidence that hydroxychloroquine reduced patients’ chances of being placed on a mechanical ventilator and that the drug was associated with 'increased overall mortality.'

A research trial by Brazilian scientists was halted early for safety reasons after patients taking a relatively high dose of chloroquine developed irregular heart rates that increased their risk of a potentially fatal heart arrhythmia. Repeating what many advocates of the drug have argued, Hatfill said it was given in late stages of the virus. Patients were dying from other diseases but 'they blamed the drug,' he said."

washingtonpost.com/politics/20

The Washington Post · Scientist who was part of covid treatment controversy returns to HHSBy Lena H. Sun
Public
Omega_Scribet

'Boetes voor off-label voorschrijven medicijnen aan Covidpatiënten gehalveerd'

"De artsen schreven de off-label medicijnen hydroxychloroquine en/of ivermectine aan patiënten met Covid-19 voor. "

"Een huisarts kan een geneesmiddel off-label voorschrijven als er protocollen en standaarden zijn of in ontwikkeling zijn die het voorschrijven van zulke geneesmiddelen toelaten. Dat was hier niet het geval. Er was juist een advies van de Nederlandse beroepsvereniging van huisartsen dat het gebruik van deze twee geneesmiddelen voor COVID-19 afraadde."

"De boetes zijn gezien de uitzonderlijke omstandigheden tijdens de coronapandemie echter niet evenredig, oordeelt de Afdeling bestuursrechtspraak. Daarom halveert de Afdeling bestuursrechtspraak de boetes."

skipr.nl/nieuws/boetes-voor-of

Skipr · Boetes voor off-label voorschrijven medicijnen aan Covidpatiënten gehalveerd - SkiprDe minister van Volksgezondheid, Welzijn en Sport (VWS) heeft vier artsen terecht een boete opgelegd vanwege het off-label voorschrijven van medicijnen aan patiënten met COVID-19. Wel halveert de Raad van State de boetes gezien de uitzonderlijke omstandigheden in de Covid-19 periode.
#zorg#RaadVanState#covid19
Public *
Pascal Hingamp

This has somehow slipped under my radar: "Controversial #COVID study that promoted unproven treatment retracted after four-year saga - Paper on #hydroxychloroquine led by French researcher Didier #Raoult is second-most-cited study ever to be withdrawn."
"Overall, the IHU now has 32 retracted papers — 28 of them authored by Raoult — and 230 other studies with expressions of concern."
doi.org/10.1038/d41586-024-040 #IHU #HCQ #retraction #Marseille #AMU

Screen shot of the retracted article on the publisher's website (Elsevier)
Public
DrBob, Neurologist, 🧠Mechanic

A discredited study that set off a flurry of interest in using an antimalarial drug to treat COVID-19 has now been formally withdrawn

A scientific journal on Tuesday retracted the March 2020 study that introduced the world to #hydroxychloroquine early in the #COVID-19 pandemic and confirmed that the attention was undeserved from the start

The antimalarial drug was briefly touted as a possible treatment for the #coronavirus at a time when little else was available…fellow scientists quickly raised doubts about the study's size, scientific flaws and ethics. Follow-up studies failed to confirm its findings.

usatoday.com/story/news/health

USA TODAY · Study retracted years after it set off an infamous COVID-19 treatment scandalBy , USA TODAY
Public
Benjamin Carr, Ph.D. 👨🏻‍💻🧬

Nature magazine reports that "A study that stoked enthusiasm for the now-disproven idea that a cheap malaria #drug can treat #COVID19 has been retracted — more than four-and-a-half years after it was published."

Controversial #COVID study that promoted unproven treatment retracted after four-year saga
Paper on #hydroxychloroquine led by French researcher Didier Raoult is second-most-cited study ever to be withdrawn.
nature.com/articles/d41586-024

www.nature.comControversial COVID study that promoted unproven treatment retracted after four-year sagaPaper on hydroxychloroquine led by French researcher Didier Raoult is second-most-cited study ever to be withdrawn.
Public
ResearchBuzz: Firehose

Boing Boing: 2020 paper pushing bogus Covid treatment finally retracted. “A 2020 paper that caused a shortage of an anti-malarial drug also used to treat autoimmune disorders like lupus was just retracted by the journal that published it. In March of 2020, during the height of the COVID-19 pandemic, the International Journal of Antimicrobial Agents published a study claiming […]

https://rbfirehose.com/2024/12/19/boing-boing-2020-paper-pushing-bogus-covid-treatment-finally-retracted/

ResearchBuzz: Firehose | Individual posts from ResearchBuzz · Boing Boing: 2020 paper pushing bogus Covid treatment finally retracted | ResearchBuzz: Firehose
More from ResearchBuzz: Firehose
#coronavirus#COVID19#drugs
Public
Grégory Gutierez 🌻

"L'étude Gautret était "la pierre angulaire d'un scandale mondial" et sa rétractation "constitue une reconnaissance tardive mais essentielle des dérives scientifiques qui ont mené à la mise en danger des patients", a salué dans un communiqué la Société française de pharmacologie et de thérapeutique. La SFPT a aussi appelé à une remise en question plus large des travaux menés sous la tutelle du professeur #DidierRaoult, en particulier sur l'#hydroxychloroquine."

francetvinfo.fr/sante/maladie/

Franceinfo · Covid-19 : l'étude fondatrice du professeur Didier Raoult sur l'hydroxychloroquine officiellement invalidéeBy franceinfo avec AFP
Public
Grégory Gutierez 🌻

"Je suis frappée de voir que chaque fois qu'il monte au créneau, c'est avec des raisonnements complotistes. Cette accumulation dresse le portrait de quelqu'un qui ne comprend pas comment on fait évoluer les connaissances dans le monde de la science." Dominique Costagliola, épidémiologiste et directrice de recherche à l'institut Pierre-Louis
#PatrickHetzel #hydroxychloroquine #homéopathie #DidierRaoult #vaccin
francetvinfo.fr/politique/gouv

Franceinfo · Hydroxychloroquine, vaccins, homéopathie... Patrick Hetzel, un ministre de l'Enseignement supérieur et de la RBy Linh-Lan Dao
Public
Giuseppe Michieli

#Covid19 : la #polémique sur les #décès liés à l’ #hydroxychloroquine rebondit lemonde.fr/sciences/article/20

En janvier, une équipe française avait estimé à 17 000 le nombre de morts causées dans six pays par l’administration de la molécule. Une décision qui réjouit la nébuleuse défendant le « protocole Raoult » et inquiète des pharmacologues et épidémiologistes.

Le Monde · Covid-19 : la polémique sur les décès liés à l’hydroxychloroquine rebonditBy Hervé Morin
Public
Auscandoc

Descriptions of Scientific Evidence and Uncertainty of Unproven #COVID19 Therapies in US News: Content Analysis Study infodemiology.jmir.org/2024/1/ “Most claims on #hydroxychloroquine (n=236, 79%) were offered by a “prominent person,” of which 97% (n=230) were from former US President Trump. Despite the inclusion of scientific evidence, many claims of the safety and efficacy were made by nonexperts. Few news reports expressed scientific uncertainty in discussions of unproven COVID-19 therapeutics”

JMIR InfodemiologyDescriptions of Scientific Evidence and Uncertainty of Unproven COVID-19 Therapies in US News: Content Analysis StudyBackground: Politicization and misinformation or disinformation of unproven COVID-19 therapies have resulted in communication challenges in presenting science to the public, especially in times of heightened public trepidation and uncertainty. Objective: This study aims to examine how scientific evidence and uncertainty were portrayed in US news on 3 unproven COVID-19 therapeutics, prior to the development of proven therapeutics and vaccines. Methods: We conducted a media analysis of unproven COVID-19 therapeutics in early 2020. A total of 479 discussions of unproven COVID-19 therapeutics (hydroxychloroquine, remdesivir, and convalescent plasma) in traditional and online US news reports from January 1, 2020, to July 30, 2020, were systematically analyzed for theme, scientific evidence, evidence details and limitations, safety, efficacy, and sources of authority. Results: The majority of discussions included scientific evidence (n=322, 67%) although only 24% (n=116) of them mentioned publications. “Government” was the most frequently named source of authority for safety and efficacy claims on remdesivir (n=43, 35%) while “expert” claims were mostly mentioned for convalescent plasma (n=22, 38%). Most claims on hydroxychloroquine (n=236, 79%) were offered by a “prominent person,” of which 97% (n=230) were from former US President Trump. Despite the inclusion of scientific evidence, many claims of the safety and efficacy were made by nonexperts. Few news reports expressed scientific uncertainty in discussions of unproven COVID-19 therapeutics as limitations of evidence were infrequently included in the body of news reports (n=125, 26%) and rarely found in headlines (n=2, 2%) or lead paragraphs (n=9, 9%; P<.001). Conclusions: These results highlight that while scientific evidence is discussed relatively frequently in news reports, scientific uncertainty is infrequently reported and rarely found in prominent headlines and lead paragraphs.
Public
Auscandoc

Misinformation, Trust, and Use of #Ivermectin and #Hydroxychloroquine for #COVID19 jamanetwork.com/journals/jama- jamanetwork.com/journals/jama- “Among 13 438 adults.., 6% reported use of either ivermectin or hydroxychloroquine. Those who endorsed COVID-19 vaccine–related #misinformation, had lower trust in hospitals and physicians and lower trust in scientists, and exhibited greater belief in #conspiracy theories were more likely to report using one of these medicines. #MisinformationKills

jamanetwork.comMisinformation, Trust, and Use of Ivermectin and Hydroxychloroquine for COVID-19This survey study examines the association between non–evidence-based treatment for COVID-19 and endorsement of misinformation and trust in institutions among US residents with prior COVID-19 infection.
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